Rat striatum

Videos demonstrate that vector spread in young and old rats is dependent on capsid and age of rats. Vector in this case refers to an agent (here a modified virus) that conveys genetic material into a targeted group of cells. These videos were made for a lab researching treatments for Parkinson disease to demonstrate how far and well the vector spread and was taken up by cells after injection. These use an MRI stack from NITRC and data from immunohistochemical-positive cell counts from the Manfredsson laboratory.

Comparison of two vector capsid variations.

Transfusion in young rats with no vector capsid variation.

Human precuneus

Videos model an anatomical area of the human brain. These use an MRI stack from NITRC and a custom clearing algorithm with false coloring to highlight one section of the brain.

saggital spin

coronal spin